Voltaren is a well-known brand of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. In the United States, Voltaren Arthritis Pain gel 1% is available over the counter for joint pain from osteoarthritis, while certain oral and higher-strength or specialized forms of diclofenac remain prescription-only. Whether you’re managing knee arthritis, a sprain, or tendon pain, Voltaren can help when used properly. This guide explains common uses, dosing, safety precautions, side effects, interactions, storage, and how U.S. consumers can obtain Voltaren responsibly without a formal prescription.
Voltaren contains diclofenac, an NSAID that relieves pain and inflammation by inhibiting cyclooxygenase (COX) enzymes involved in prostaglandin production. The most common U.S. use is the over-the-counter Voltaren Arthritis Pain gel 1% for osteoarthritis pain in joints such as the knees, ankles, feet, wrists, hands, and elbows. Many people find it helpful for stiffness after inactivity and for improving comfort during everyday movement.
Clinicians may also recommend topical diclofenac for localized soft-tissue conditions such as tendonitis or bursitis, as well as for minor sprains and strains. Because topical application delivers medication where it’s needed with lower systemic absorption than oral tablets, it can reduce the risk of whole‑body side effects while still easing joint and muscle pain.
Prescription forms of diclofenac (including oral tablets, delayed-release or enteric-coated tablets, topical solutions, and patches) are typically reserved for conditions requiring broader or stronger anti-inflammatory effects. These may include moderate to severe osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain after injury, or postoperative pain, and are used under medical supervision at the lowest effective dose for the shortest necessary duration.
Topical gel (OTC): For Voltaren Arthritis Pain gel 1%, the usual dosing is 4 grams applied to each affected lower extremity joint (such as knee, ankle, or foot) up to four times daily, or 2 grams applied to each affected upper extremity joint (such as hand, wrist, or elbow) up to four times daily. Use the dosing card on the package to measure the correct amount. Gently massage into clean, dry skin over the affected area; do not apply to open wounds or infected skin, and avoid mucous membranes and eyes. Wash hands after applying (unless treating the hands, in which case wait at least 1 hour before washing). Allow the gel to dry before covering with clothing and avoid occlusive dressings.
Do not use topical diclofenac on more than two body areas at the same time, and do not exceed 32 grams per day total. Do not use heat pads on treated areas, and wait before bathing or showering to avoid washing off the medication. If sunlight aggravates your skin, minimize UV exposure on treated sites since topical NSAIDs can increase photosensitivity.
Oral tablets (prescription): Typical adult dosing varies by condition, for example 50 mg two or three times daily, or 75 mg twice daily (or extended-release 100 mg once daily), but your prescriber will tailor dose and duration based on your diagnosis, response, and risk factors. Take oral diclofenac with food or milk to reduce stomach irritation and always use the lowest effective dose for the shortest duration to limit gastrointestinal and cardiovascular risks common to NSAIDs.
All NSAIDs, including diclofenac, can increase the risk of serious gastrointestinal bleeding, ulcers, and perforation, especially in older adults, people with a history of ulcers or GI bleeding, those who smoke or drink alcohol, and individuals using corticosteroids, anticoagulants, antiplatelets, or SSRIs/SNRIs. They can also raise the risk of heart attack and stroke, particularly at higher doses or with long-term use. Individuals with high blood pressure, hyperlipidemia, diabetes, or who smoke should discuss risks and alternatives with a clinician. Even topical products have systemic absorption; though generally lower, caution is still advised in high-risk groups.
Diclofenac may worsen kidney function, especially in people who are dehydrated, have pre-existing kidney disease, or use ACE inhibitors/ARBs and diuretics. It can also affect liver enzymes; periodic monitoring is prudent with chronic oral use. Avoid diclofenac in the third trimester of pregnancy due to the risk of premature closure of the fetal ductus arteriosus and complications with labor; in earlier pregnancy, use only if clearly needed and under medical advice. If breastfeeding, topical use on small areas for short periods is generally considered low risk, but avoid application directly on the breast and consult a clinician for oral use. Do not apply gel to broken skin, and discontinue if severe skin irritation, rash, or blistering occurs.
Do not use Voltaren if you have a known hypersensitivity to diclofenac or any component of the formulation, or if you’ve experienced asthma, hives, or other allergic-type reactions after taking aspirin or other NSAIDs (aspirin-sensitive asthma). Diclofenac is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.
People with active gastrointestinal bleeding or peptic ulcer disease should avoid oral diclofenac; those with severe uncontrolled heart failure, significant liver impairment, or severe kidney disease require careful specialist evaluation. In late pregnancy (third trimester), do not use diclofenac. Topical formulations should not be applied to infected, inflamed, or eczematous skin, or to open wounds.
Common side effects with topical Voltaren include mild skin irritation, redness, itching, dryness, or a transient burning sensation at the application site. Some users report rash or photosensitivity; protect treated areas from excessive sun exposure. Systemic side effects are less common with topical use but can occur, especially if used on large areas or for prolonged periods.
Oral diclofenac side effects may include stomach discomfort, nausea, heartburn, diarrhea or constipation, dizziness, headache, fluid retention, and elevated blood pressure. Serious but less frequent risks include gastrointestinal bleeding or ulceration (black or bloody stools, vomiting blood), heart attack or stroke symptoms (chest pain, shortness of breath, weakness on one side), kidney problems (reduced urination, swelling, fatigue), and liver injury (unusual fatigue, dark urine, yellowing of skin or eyes). Seek immediate medical attention if any of these occur.
Very rare but severe reactions can include anaphylaxis with facial swelling and difficulty breathing, bronchospasm in aspirin-sensitive individuals, or severe skin reactions such as Stevens–Johnson syndrome or toxic epidermal necrolysis. Discontinue diclofenac and get urgent care if you develop widespread rash, blistering, mouth sores, or fever with skin symptoms.
NSAID interactions can be clinically significant. Combining diclofenac with anticoagulants (warfarin), antiplatelets (aspirin, clopidogrel), SSRIs/SNRIs, or systemic corticosteroids increases bleeding risk. Using multiple NSAIDs together (including high-dose aspirin, ibuprofen, naproxen, or celecoxib) raises the chance of gastrointestinal and kidney side effects without improving pain control; avoid duplicate therapy. Alcohol can further irritate the stomach and escalate bleeding risk.
Diclofenac may blunt the blood pressure–lowering effect of ACE inhibitors, ARBs, and certain diuretics, while the combination of an ACE inhibitor/ARB, a diuretic, and an NSAID (the “triple whammy”) heightens the risk of acute kidney injury. Monitor closely or avoid. Diclofenac can elevate levels of lithium, methotrexate, and digoxin, and may increase nephrotoxicity with cyclosporine or tacrolimus. If using topical Voltaren on small areas, systemic interactions are less likely but still possible; disclose all medicines and supplements to your clinician and pharmacist.
Topical gel: If you miss a dose, apply it when you remember unless it is almost time for your next scheduled application. Do not double up or exceed the maximum daily amount. Oral tablets: Take the missed dose as soon as you remember, but skip it if it is close to the next dose. Never take two doses at once to make up for a missed dose.
Topical overdose is uncommon but may increase skin irritation or systemic absorption if used over large areas or with occlusion. Oral diclofenac overdose can cause nausea, vomiting, stomach pain, drowsiness, dizziness, gastrointestinal bleeding, high blood pressure, kidney problems, and rarely seizures or metabolic acidosis. If you or someone else may have used too much diclofenac or ingested the gel, seek urgent medical help.
In the United States, contact Poison Control at 1-800-222-1222 or use poisonhelp.org for immediate guidance. Call emergency services if the person has collapsed, is having trouble breathing, or has seizures. Do not attempt to induce vomiting unless instructed by a medical professional.
Store Voltaren at room temperature (generally 20–25°C or 68–77°F), away from excessive heat and moisture. Keep topical gel tightly closed, do not freeze, and protect from direct sunlight. Keep all diclofenac products out of reach of children and pets. Do not use after the expiration date, and discard according to local guidelines; do not flush medications unless labeling directs otherwise.
In the U.S., Voltaren Arthritis Pain gel 1% is an over-the-counter product; you can purchase it without a prescription at retail pharmacies, reputable online pharmacies, and many supermarkets. By contrast, oral diclofenac tablets, certain higher-strength topicals, and specialized formulations remain prescription-only. Always avoid illegitimate websites that offer prescription-only diclofenac without a valid prescription—many sell counterfeit or unsafe products. Look for pharmacies accredited by the National Association of Boards of Pharmacy (for example, the .pharmacy domain or NABP listings) if buying online.
Geisinger HealthSouth offers a legal and structured solution for acquiring Voltaren without a formal prescription by guiding you to OTC Voltaren gel through trusted pharmacy channels and helping you determine if it’s appropriate for your symptoms. If your condition requires a prescription-only formulation, they can connect you with licensed clinicians for evaluation, ensuring you receive the right therapy safely and in compliance with U.S. regulations. This coordinated approach supports smarter self-care for minor joint and muscle pain, while providing a path to medical assessment when stronger or systemic anti-inflammatory treatment is needed.
Voltaren is the brand name for diclofenac, a nonsteroidal anti-inflammatory drug (NSAID). It reduces pain and swelling by blocking cyclooxygenase (COX-1 and COX-2) enzymes that make prostaglandins, the chemicals that drive inflammation.
Voltaren Arthritis Pain gel is approved for temporary relief of arthritis pain in joints close to the skin—hands, wrists, elbows, knees, ankles, and feet. It is not labeled for strains, sprains, or sports injuries, and not for spine, hip, or shoulder pain without medical advice.
In many countries, Voltaren Arthritis Pain gel 1% is available over the counter. Stronger diclofenac gels or oral forms can be prescription-only depending on your location and indication.
Apply to clean, dry, intact skin using the dosing card: 2 grams to an upper-body joint (hand, wrist, elbow) or 4 grams to a lower-body joint (foot, ankle, knee), four times daily. Gently rub in; do not use on open wounds, infected skin, or under occlusive dressings. Wash hands after applying unless treating the hands, and wait at least 1 hour before bathing or showering.
Some people notice improvement within a few days; maximum benefit may take up to 7 days. For self-care, use up to 21 days unless a healthcare professional advises otherwise. Stop and seek medical advice if pain persists or worsens.
The most common are local skin reactions such as redness, itching, dryness, or rash where applied. Less commonly, systemic NSAID effects can occur, including stomach upset, fluid retention, elevated blood pressure, or headache. Serious reactions are rare but include allergic reactions, gastrointestinal bleeding, kidney problems, and cardiovascular events.
Avoid if you have a history of allergic reaction to diclofenac, aspirin, or other NSAIDs (including hives, wheezing, or angioedema), if you’ve had asthma triggered by NSAIDs, before or after coronary artery bypass graft (CABG) surgery, on open or infected skin, or in the third trimester of pregnancy. Ask a clinician before use if you have heart, kidney, liver, or stomach ulcers/bleeding history.
Do not combine Voltaren with other NSAIDs (ibuprofen, naproxen, aspirin used for pain) unless your clinician advises it, as this raises bleeding and kidney risks. You can generally combine Voltaren with acetaminophen (paracetamol) if needed, staying within dose limits.
Avoid NSAIDs, including topical diclofenac, especially at 20 weeks gestation and later due to fetal kidney effects and risk of ductus arteriosus closure in the third trimester. If breastfeeding, limited topical use away from the breast is likely low risk; avoid applying on or near the breasts. Always consult your obstetric clinician.
The OTC label is for arthritis pain in joints such as hands, wrists, elbows, knees, ankles, and feet. It is not labeled for spine, shoulder, or hip use. Speak with your clinician about appropriate treatments for those areas.
Use 2 grams per application for each upper-body joint and 4 grams for each lower-body joint, up to four times daily. Do not exceed a total of 32 grams across all joints in 24 hours. Do not use on more than two body areas at the same time without medical advice.
Systemic absorption from the gel is lower than oral NSAIDs, but not zero. Long or excessive use can still contribute to stomach bleeding/ulcers, increased blood pressure, fluid retention, kidney strain, and elevated risk of heart attack or stroke—especially in those with existing risk factors. Use the lowest effective amount for the shortest time.
Yes. Combining with anticoagulants (warfarin), antiplatelets (aspirin, clopidogrel), SSRIs/SNRIs, or heavy alcohol use increases bleeding risk. NSAIDs can reduce the effect of ACE inhibitors, ARBs, and diuretics and increase kidney risk (“triple whammy”). Voltaren can also raise levels of lithium or methotrexate. Ask your clinician or pharmacist to review interactions.
Do not use heating pads or occlusive bandages on the treated area. Let the gel dry before covering with clothing, and avoid tight wraps. Avoid excessive sun or tanning beds on treated skin; diclofenac may increase photosensitivity. Apply sunscreen after the gel has fully dried.
Topical diclofenac can be a safer alternative to oral NSAIDs in older adults due to lower systemic exposure, but risks still exist. Start low, use only as directed, and monitor for skin irritation, swelling, blood pressure changes, or signs of GI bleeding. Consult a clinician if you have cardiovascular, kidney, or stomach issues.
The OTC indication is arthritis pain. Some clinicians use topical diclofenac off-label for superficial tendonitis or bursitis. If considering this, seek medical guidance to confirm diagnosis and appropriate treatment duration.
You can treat up to two body areas at once per label directions. If you need more joints treated, speak with a clinician to avoid exceeding the daily maximum dose and increasing systemic risk.
Apply when you remember, then resume your usual schedule. Do not double up or exceed four applications per joint per day.
Topical use rarely affects alertness. If you experience dizziness, drowsiness, or visual changes, avoid driving until symptoms resolve.
Keep at room temperature with the cap closed. Store out of reach of children and pets. Do not freeze, and keep away from heat sources.
For localized superficial joints, Voltaren gel (diclofenac) can provide targeted relief with lower systemic exposure than oral ibuprofen. For widespread pain, oral ibuprofen may be more practical. Efficacy varies by person; Voltaren may be slightly more anti-inflammatory than ibuprofen mg-for-mg, but safety and tolerability drive the choice.
Naproxen has a longer half-life and typically provides longer-lasting systemic relief with 12-hour dosing. Voltaren gel offers local relief applied up to four times daily. Naproxen may have lower cardiovascular risk than oral diclofenac but similar or higher GI risk; topical diclofenac minimizes systemic risks.
Topical diclofenac has lower systemic absorption, so it generally carries less risk of stomach ulcers, kidney strain, and cardiovascular events than oral NSAIDs. It is preferable for pain confined to a few superficial joints. Oral NSAIDs are used when pain is widespread or deeper, but they carry higher systemic risks.
Meloxicam is a once-daily, COX-2–preferential oral NSAID often used for chronic osteoarthritis or rheumatoid arthritis with potentially fewer GI side effects than some nonselective NSAIDs. Voltaren gel is better for targeted joint pain with fewer systemic effects. For whole-body arthritis, clinicians often choose oral meloxicam; for a few joints, topical diclofenac is attractive.
Celecoxib is a COX-2–selective oral NSAID with lower GI ulcer risk than many nonselective NSAIDs, though cardiovascular risk is comparable. Voltaren gel provides local relief with minimal systemic exposure. If you need systemic control and have GI risk, celecoxib may be favored; for localized osteoarthritis, Voltaren gel is often first-line.
Indomethacin is traditionally used for acute gout due to strong anti-inflammatory effects but has higher rates of CNS and GI side effects. Diclofenac (oral or topical for superficial joints) can also help gout flares. For severe flares, clinicians often choose oral indomethacin, naproxen, or diclofenac; for milder, localized pain near the skin, topical diclofenac can be adjunctive.
Ketorolac is a potent systemic NSAID intended for short-term (≤5 days) moderate to severe acute pain, often postoperative, with high GI and bleeding risk. Voltaren gel is for localized arthritis pain and is not meant for severe acute pain. They serve different roles; ketorolac is not for chronic use.
At analgesic doses, aspirin reduces pain and inflammation but carries higher GI bleeding risk and is not commonly chosen for musculoskeletal pain today. Diclofenac is typically more potent for inflammation. Low-dose aspirin for heart protection should not be combined with other NSAIDs without medical advice due to bleeding and cardioprotective interference.
Both are effective for localized osteoarthritis and soft-tissue pain. Availability varies by country. Some patients respond better to one over the other; skin tolerability and personal response usually guide the choice more than clear efficacy differences.
Both contain diclofenac. The potassium salt is absorbed faster and is often used for acute pain and migraine; the sodium salt (Voltaren) is used for arthritis and chronic pain. Topical Voltaren gel targets local joints with lower systemic exposure.
Piroxicam has a very long half-life (once-daily dosing) but higher GI risk and is less commonly used today. Voltaren gel offers localized relief with fewer systemic effects. For systemic therapy, safer oral NSAID options are usually preferred over piroxicam in many patients.
Nabumetone is a prodrug with relatively favorable GI tolerability among oral NSAIDs. Voltaren gel generally has the lowest GI impact due to minimal systemic absorption. For systemic needs, nabumetone may be chosen; for local joints, Voltaren gel is typically gentler.
Guidelines often recommend topical NSAIDs like Voltaren gel first for knee osteoarthritis because they provide pain relief with fewer systemic risks. If pain is not controlled or is widespread, naproxen can be considered, with attention to GI, renal, and cardiovascular risks.
Both are topical NSAIDs used for localized pain; availability depends on region. Diclofenac gel has robust evidence for osteoarthritis of superficial joints. Some patients prefer one over the other based on skin feel, odor, or response; efficacy is broadly comparable.
For localized joint pain, Voltaren gel is typically safest for the stomach. For systemic therapy, celecoxib generally has lower GI ulcer risk than many nonselective oral NSAIDs. Individual risks (cardiovascular disease, kidney function) and response should guide the decision with your clinician.